Journal of Pharmaceutics & Drug Delivery ResearchISSN: 2325-9604

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Arulmozhi Author

Arulmozhi@gmail.com

Subjects of specialization
Liquid chromatography mass spectrometry; Rizatriptan benzoate; Genotoxic impurities

Affiliation
Department of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth University, Erandwane, Pune, India

Biography

Arulmozhi Department of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth University, Erandwane, Pune, India

Publications

Research Article Subscription

Indian Propolis Loaded Folic Acid Conjugated PLGA Nanoparticles: Formulation Development, Characterization, In Vitro and In Vivo Anticancer Study

Author(s):

Harshad S Kapare, Sathiyanarayanan L, Arulmozhi and Mahadik KR

Propolis, a natural bee hive product is well proven for its anticancer potential due its various polyphenols and flavonoids constituents. Anticancer efficacy of propolis is limited due to its poor water solubility and bioavailability. The present study is investigated for design and development of ethanolic extract of Indian propolis (EEIP) loaded folic acid conjugated Poly (D,L-lactide-co-glycolide) nanoparticles (denoted as ELFPN) were investigated to achieve improved solubility, sustained drug release and to study synergized anticancer efficacy. Formulation development, characterization and optimization were carried out by design of experiment approach. . In vitro and in vivo cytotoxicity study was carried out for optimized formulation. Developed ELFPN sh... view more»

DOI: 10.4172/2325-9604.1000164

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