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Hindi Journal of Applied Bioinformatics & Computational BiologyISSN: 2329-9533
Arun G Ingale Author
Subjects of specialization
Affiliation
Bioinformatics, Nanotechnology, Proteomics , Bioinformatics, Bionanotechnology
Department of Biotechnology, School of Life Sciences, North Maharashtra University, Jalgaon, MS, 425001, India
Biography
Arun G Ingale is currently working in teh Department of Biotechnology, School of Life Sciences, Kavayitri Bahinabai Chaudhari, North Maharashtra University, Jalgaon, INDIA. He persude his M.Sc. PhD, NET, FSSc, FMIF in Japan. He worked in the Department Biotechnology from KBC North Maharashtra University, Jalgaon. He is expertize in Genomics, Proteomics and Bioinformatics, Bionanotechnology
Publications
Research Article Subscription
Homology Modeling and Structural Validation Studies of 3 Oxoacyl (Acyl Carrier Protein) Synthase II and Dihydropteroate Synthase Protein of Neisseria meningitides
Author(s): Vaibhav Sabale and Arun G Ingale
Objective: Neisseria meningitidis (NM) is foremost causative agent of bacterial meningitis. The two very important protein has been selected for the study of homology modeling and structural validation in Neisseria meningitis. The 3 oxoacyl (acyl carrier protein) synthase II (3OASII) enzyme which involved in fatty acid biosynthesis of Neisseria meningitidis. This enzyme in fatty acid synthesis and target for discovery of novel antibacterial agent. Dihydropteroate synthase (DHPS), an enzyme plays an acute role in the bacterial folate metabolism which catalyzes the development of 7, 8- dihydropteroate from p-aminobenzoic acid (pABA) and 6- hydroxymethyl-7, 8-dihydropterin-pyrophosphate (DHPP). The absence of the folate pathway in higher eukary... view more»
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