Journal of Pharmaceutics & Drug Delivery ResearchISSN: 2325-9604

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Arun Kumar Chopra Author

Subjects of specialization
Corneal permeability.

Affiliation
Department of Pharmaceutical Sciences, Maharshi Dayanand University, India

Biography

My name is  Arun Kumar Chopra-  I am from Department of Pharmaceutical Sciences, Maharshi Dayanand University, India  My area of interests are Corneal permeability.                                                                       


Publications

Research Article Subscription

Box-Behnken Designed Fluconazole Loaded Chitosan Nanoparticles for Ocular Delivery

Author(s):

Arun Kumar Chopra, Rakesh Kumar Marwaha, Deepak Kaushik and Harish Dureja

Box-Behnken Designed Fluconazole Loaded Chitosan Nanoparticles for Ocular Delivery

The present study aimed to develop chitosan nanoparticles containing Fluconazole for ocular delivery using Box-Behnken design. The Fluconazole loaded chitosan nanoparticles were prepared by an ionic gelation method using Sodium tripolyphosphate (NaTPP) as cross linking agent. The effect of the factors - concentration of chitosan (x1), concentration of NaTPP (x2) and volume of NaTPP (x3) was studied on release of drug from nanoparticles. The results revealed that entrapment efficiency was highest at low level of chitosan concentration, high level of NaTPP concentration and low levels of NaTPP volume... view moreĀ»

DOI: 10.4172/2325-9604.1000121

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