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Awaad A Radwan Author
Subjects of specialization
Affiliation
Applied Microbiology, Applied Microscopy, Applied Mycology, Applied Physiology, Biomedical Research
King Saud University, Saudi Arabia, got his BSc and MSc from Faculty of Pharmacy
Biography
Awaad A Radwan has completed his PhD from Kitasato University, Tokyo, Japan in 2002. He is the professor of King Saud University, Saudi Arabia. He has over 60 publications that have been cited over 400 times, and his publication H-index is 9 and has been serving as peer reviewer member of reputed Journals.
Publications
Short Communication Open Access
In-silico database screening for anti-virulent-inhibitors of staphylococcus aureus histidine kinase
Author(s): Awaad A Radwan
Bacterial histidine kinases (HKs) not only govern adaptive responses of the bacteria organisms but also these kinases are unique. So, HKs are attractive drug targets to control bacterial infections. The 3D structure of S. aureus HK was not isolated in high-resolution coordinates. Virtual screening database (VS) search is a modern tools that succeeded to discover several drugs to the market. S. aureus HKs inhibitros are promising antibiotics however, there is no drug in the market and few inhibitor compounds are reported. We were prompted to the use of database VS tools to discover novel HKs/Wak inhibitors. The homology modeling, molecular docking studies and molecular dynamics (MD) simulations were applied to construct target-ligand complex. The obtained complex was ap... view more»
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