B Madhusudhana Rao Author

Case Report Open Access

Diffuse Brain Injury-Review of Literature and Representative Case Reports

Author(s):

Ajaya Kumar A and B Madhusudhana Rao

Review of Literature: Diffuse brain injury includes diffuse axonal injury (DAI), diffuse vascular injury, hypoxic-ischemic injury and brain swelling. Adams described three grades of DAI. Diffuse vascular injury is usually incompatible with life. Ischemic hypoxia results in hemispheric hypodensity. Cerebral hemispheric swelling has the highest mortality.

 Administration of mannitol, hyperventilation for short duration and infusion of barbiturate are useful to control ICP. Decompressive craniectomy is recommended in patients with severe brain edema. Transgastric jejunal feeding and early tracheostomy are recommended in ventilated patients. Cognitive rehabilitation therapy (CRT) is the fundamental compo... view more»

DOI: 10.4172/0032-745X.1000291

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