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Hindi Clinical Oncology: Case Reports
Baruch Brenner Author
Subjects of specialization
Affiliation
cancer, cancer oncology, Carcinogenesis
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Biography
Dr. Baruch Brenner is working as scientist and professor at DSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. The author has specalization in cancer, cancer oncology, chemotherapy, Carcinogenesis, Chemotherapy
Publications
Case Report Open Access
Carboplatin-induced Allergic Coronary Vasospastic Reaction (Kounis Syndrome)
Author(s): Osnat Itzhaki Ben Zadok, Inbar Nardi Agmon, Pablo Codner, Alona Zer, Baruch Brenner, Ran Kornowski, and Katia Orvin
We describe a case of carboplatin-induced allergic coronary vasospastic reaction manifesting as ST-elevation myocardial infarction (Kounis syndrome) in a 67-year old male with lung adenocarcinoma and underlying ischemic heart disease. Shortly after commencing his 2nd carboplatin cycle, the patient presented with acute bronchospasm and hemodynamic collapse, anterolateral ST-elevations, elevated cardiac biomarkers and apical akinesia. Following initial management with high-dose steroids, a coronary angiography was performed demonstrating obstructive lesion in his left anterior descending artery which was treated with percutaneous coronary intervention and stent placement. The patient demonstrated significant clinical improvement. This case highlights the diagnostic work-up and ... view more»
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