Journal of Clinical & Experimental OncologyISSN: 2324-9110

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Carlos Rocha Oliveira Author

Subjects of specialization
Mucoepidermoid carcinoma, Breast cancer, Facial tumour, Rickets

Affiliation
School of Health Sciences, Universidade Anhembi Morumbi, S

Biography

Carlos Rocha Oliveira was working in the School of Health Sciences, Universidade Anhembi Morumbi, São Paulo/SP, Brazil.  He has more than 40 publications. His current research area related to osteoarthropathy


Publications

Short Communication Open Access

In vitro Study of Anti-Leukemic Potential of Ursolic Acid in Jurkat Cell Line

Author(s):

Ricardo Kenji Iguchi Panucci, Alexandre Mellitto, Carlos Rocha Oliveira, Welker de Mello Marin and Claudia Bincoletto

This study aims to assess the possible antitumor effects of the Ursolic Acid through cell death studies. Hence, Jurkat cell lines related to leukemia were subjected to treatment with different concentrations of the Ursolic Acid in order to identify their likely mechanism of death. After completion of cell viability tests, we suggest that this acid used in this study have antiproliferative/ cytotoxic activity in a dose-dependent manner. The results obtained indicate that the Ursolic Acid assessed in this study have cytotoxic activity with IC50% value of 10 μM. In addition, we observed that the IC50% value tested o... view moreĀ»

DOI: 10.4172/2324-9110.1000161

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