International Journal of Ophthalmic PathologyISSN: 2324-8599

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Cathryn Anne Scott Author

scott@uniud.it

Subjects of specialization
Cancer Biology, Cancer Diagnostics, Diabetes Mellitus

Affiliation
Department of Medical and Biological Sciences, Institute of Anatomic Pathology,Faculty of Medicine, University of Udine, Italy

Biography

Dr. Cathryn Anne Scott currently working as Researcher in department of Medical and Biological Sciences at University of Udine, Italy. Dr. Cathryn Anne Scott research focuses on Cancer Biology, Cancer Diagnostics, Type 1 Diabetes Mellitus.

Publications

Research Article Subscription

Cultured Human Keratocytes from the Limbus and Cornea Both Express Epithelial Cytokeratin 3: Possible Mesenchymal-Epithelial Transition

Author(s):

Giuseppina Perrella, Cathryn Anne Scott, Renza Spelat, Paolo Brusini, Federica D?Aurizio, Ilaria De Pol and Harminder Singh Dua

The corneal limbus is the repository of epithelial stem cells (SC) that sustain the turnover of corneal epithelial cells. The limbus stroma contains mesenchymal SC that generates stromal keratocytes. Mesenchymal-epithelial transition is a phenomenon wherein cells of mesenchymal phenotype can transdifferentiate to epithelial phenotype. Our aim was to study whether limbal keratocytes, cytokeratin 3 (CK3) negative, could be induced to transdifferentiate into CK3 positive cells.

Human keratocytes were isolated from the limbus and cornea of cadaver donors, cultured and evaluated for CD3... view more»

DOI: 10.4172/2324-8599.1000101

Abstract HTML PDF Supplementary File

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