Ching-Fang Chang Author

Editorial Open Access

Enrichment and Characterization of 2 Subgroups of Committed Osteogenic Cells within the Mouse Endosteal Bone Marrow with Expression Levels of CD24

Author(s):

Ching-Fang Chang

Primary osteogenic cells are acknowledged to reside at intervals the CD45- CD31- Ter119- Sca-1- cell fraction, notably within the CD51+ universe. However, careful determination of the frequency of osteogenic cells at intervals this Sca-1- cell population remains nonetheless to be determined. additionally, it's not clear that alternative cell surface markers is wont to more sub-fractionate this Sca-1- CD51+ osteogenic cell population and to outline their organic process stages. during this report, each Sca-1- CD24med and Sca-1- CD24-/lo cells are shown to be 2 tiny subsets of the Sca-1- CD51+ cell fraction. These 2 cell fractions show delicate distinction within the expression level of osteogenic marker genes like Osx and Opn, and in vitro proliferate rate. of these observations coun... view more»

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