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Hindi Journal of Clinical & Experimental OncologyISSN: 2324-9110
Claudia Bincoletto Author
Subjects of specialization
Affiliation
Mucoepidermoid carcinoma, Cancer chemotherapy, Prostate biomarker, Rickets, Survival
Department of Pharmacology, Universidade Federal de S
Biography
Claudia Bincoletto was working in the Department of Pharmacology, Universidade Federal de São Paulo - UNIFESP/EPM, SP, Brazil. He has more than 40 publications. His current research area related to osteoarthropathy.
Publications
Short Communication Open Access
In vitro Study of Anti-Leukemic Potential of Ursolic Acid in Jurkat Cell Line
Author(s): Ricardo Kenji Iguchi Panucci, Alexandre Mellitto, Carlos Rocha Oliveira, Welker de Mello Marin and Claudia Bincoletto
This study aims to assess the possible antitumor effects of the Ursolic Acid through cell death studies. Hence, Jurkat cell lines related to leukemia were subjected to treatment with different concentrations of the Ursolic Acid in order to identify their likely mechanism of death. After completion of cell viability tests, we suggest that this acid used in this study have antiproliferative/ cytotoxic activity in a dose-dependent manner. The results obtained indicate that the Ursolic Acid assessed in this study have cytotoxic activity with IC50% value of 10 μM. In addition, we observed that the IC50% value tested o... view more»
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