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Hindi Journal of Clinical & Experimental OncologyISSN: 2324-9110
Daniel Romeira Author
Subjects of specialization
Affiliation
Breast neoplasm, Lymphocytes tumor-infiltrating, Axillary lymph node
Department of Medical Oncology, Ocidental Lisbon Hospital Centre, Portugal.
Biography
Daniel Romeira was working in the Department of Medical Oncology, Ocidental Lisbon Hospital Centre, Portugal. He has more than 40 publications. His current research area related to oncology.
Publications
Review Article Subscription
Immunosurveillance in Colorectal Carcinomas with Microsatellite Instability
Author(s): Chiara Rodrigues, Daniel Romeira, Marta Pinto, Ana Massena,Helena Miranda and Ana Martins Mourao
Tumour infiltrating lymphocytes have been associated to a better prognosis in colorectal cancers. Microsatellite unstable tumours present a greater infiltration by these immune cells when comparing to microsatellite stable tumours. It has been suggested that lymphocytic infiltration may be an indicator of a host immune response against tumour cells and therefore, contribute to a better prognosis. High microsatellite instability (MSI-H) tumours have been shown to bare a better prognosis and some authors believe that TILs infiltration take a part in this. Nonetheless, the significance of tumour infiltrating lymphocytes (TILs), their distribution and prognostic value are still unclear. The aim of this review is to summarize the current evidence on tumour infilt... view more»
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