Journal of Liver: Disease & TransplantationISSN: 2325-9612

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David E. Kaplan Author

dakaplan@pennmedicine.upenn.edu 215-349-8222

Subjects of specialization
Abnormal Liver Function, Alcoholic Liver Disease, Hepatitis, Fatty Liver Diseases Autoimmune Hepatitis, Esophagogastroduodenoscopy with Botox Injection

Affiliation
Director of Hepatology, Corporal Michael J. Crescenz VA Medical Center,USA

Biography

Dr. Kaplan is board-certified in Internal Medicine, Gastroenterology and Transplant Hepatology. His clinical expertise is in cirrhosis, viral hepatitis, hepatocellular carcinoma and fatty liver. His research interests include translational research in therapy for liver cancer, epidemiological research into the relationship of medication exposures and the natural history of chronic liver disease, and clinical research related to cirrhosis. 

Publications

Research Article Subscription

Human Hepatocellular Carcinoma Metabolism: Imaging by Hyperpolarized 13C Magnetic Resonance Spectroscopy

Author(s):

Moses M. Darpolor, David E. Kaplan, Peter L. Pedersen and Jerry D. Glickson

Human Hepatocellular Carcinoma Metabolism: Imaging by Hyperpolarized 13C Magnetic Resonance
Spectroscopy

A characteristic feature of cancer cells is the alteration of their central carbon metabolism. It is generally acknowledged that for energy production cancer cells enhance their utilization of glycolysis and diminish that of oxidative phosphorylation irrespective of oxygen supply [1]. However, although mechanistic explanations for this enhanced glycolytic phenotype are controversial, it is likely due to the need for a versatile meth... view more»

DOI: 10.4172/2325-9612.1000101

Abstract HTML PDF

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