Durga Nithya Pinnamraju Author

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Fabrication of a Novel Device Containing Famotidine for Gastro Retentive Delivery Using Carbohydrate Polymers

Author(s):

Poluri Koteswari, Sajja Brahmani, Puttagunta Srinivasababu, Durga Nithya Pinnamraju and Varanasi S N Murthy

Fabrication of a Novel Device Containing Famotidine for Gastro Retentive Delivery Using Carbohydrate Polymers

The drug delivery systems that inflate in the gastric region are more appropriate for the local treatment of proximal parts of gastro intestinal tract (stomach and/or duodenum) and also drugs that are degraded in the colon, drugs with narrow absorption window and so on. The existing devices are compressible to a size suitable for swallowing and expandable to a size which will prevent passage through the pylorus. However, they put on certain trivial problems namely, composed of at least one insoluble/non-erodable synthetic polymer and one cellulosic polymer; don’t explain the ... view more»

DOI: 10.4172/2325-9604.1000130

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