Eliphaz Mukasa Author

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Instantaneous Intraoral Dispersible Rice Paper Films (IDFs): A Novel Natural Drug Delivery System

Author(s):

Eliphaz Mukasa and Danckwerts PM

At present, pharmaceutical researchers are focusing on instantaneous intraoral dispersible technologies as novel drug delivery systems because; they have outstanding advantages over the traditional oral and parenteral routes of drug administration. Some essential natural drugs have low oral bioavailability due to extensive first pass metabolism and pre systemic degradation in the gastrointestinal tract. Now, a cheap rice paper Intraoral Dispersible Film (IDF) has been developed. In this study, formulation was optimized using the experimental factorial design. The IDFs were loaded with model, natural, anti-cancer drugs, Resveratrol and Curcumin with low oral bioavailability. They were evaluated for thickness, folding endurance, swelling behaviour, among other... view more»

DOI: 10.4172/2325-9604.1000171

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