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Hindi International Journal of Ophthalmic PathologyISSN: 2324-8599
Elmohamady MN Author
Subjects of specialization
Affiliation
Phacoemulsification, Macular Degeneration, Corneal Topography, Astigmatism, Retina
Ophthalmology department, Faculty of Medicine, Benha University, Egypt
Biography
Mohamed Nagy Elmohamady currently works at the Department of Ophthalmology, Benha University. Mohamed does research in Ophthalmology. His Skills and Expertise are Clinical Ophthalmology, Cataract Surgery, Retinal Diseases, Glaucoma, Eye Diseases.
Publications
Research Article Subscription
The Role of Extracellular Matrices in Retinal Pigment Epithelial Cell Migration
Author(s): Shalaby UA, Saeed AM and Elmohamady MN
Background: To identify which extracellular matrix components modify retinal pigment epithelial cell migration and their interplay with matrix metalloproteinases in directing the behaviour of the cells in agarose droplets, an in-vitro model for cellular migration.
Methods: Migration of the cells from agarose droplets on coated tissue culture plastic (fibronectin, laminin and collagen types: I and IV) in the presence as well as absence of serum was evaluated by using phase contrast microscopy and computer analysis of captured images. Expression of metalloproteinases -1, 2 and 9 by retinal pigment epithelial cells was determined by immunocytochemistry and was confirmed by western blotting. In addition, the effect of metalloproteinases inhibitor,... view more»
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