Clinical Oncology: Case Reports

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Emily Chan (USA) Author

emily.chan@Vanderbilt.Edu

Subjects of specialization
Cancer Immunology, Immunotherapy, Cellular Immunology, Cancer Biology, Tumor Microenvironment, Clinical Oncology, Medical Oncology, Cancer Cell Biology

Affiliation
Medical Center Drive, Nashville, TN

Biography

Dr. Emily Chan is an Associate Professor of Medicine (Hematology/Oncology) Executive Medical Director for the VICC Cancer Patient Care Center Co-Chair,and Data and Safety Monitoring Committee

Publications

Case Report Open Access

Brachytherapy Boost to Tumor Bed Prior to Adjuvant Chemoradiation in Margin Positive Resected Cholangiocarcinoma

Author(s):

Satya Das*, John Kelly Wrigh, Laura Goff, Anuradha Chakravarthy and Emily Chan (USA)

Importance: The role of adjuvant therapy in resected cholangiocarcinoma patients is unproven despite poor survival rates even in completely resected patients. Most relapses occur locally and within a relatively short window from time of resection. R1 resection and lymph node positive patients are particularly at high risk for local relapse. Observation: Adjuvant modalities have not been compared head to head against one another in cholangiocarcinoma patients. The recent phase III PRODIGE 12-ACCORD 18 trial assessing adjuvant chemotherapy with gemcitabine and oxaliplatin in this group of patients was a negative study. Adjuvant radiation has been shown in some retrospective series to improve overall survival in R1 resected and lymph node positive patients. Other retrospective studies sugg... view more»

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