Enyuan Pan Author
Subjects of specialization
Affiliation
Rheumatoid arthritis, Sinomenium
Department of Pharmacy, Anhui University of Traditional Chinese Medicine, Shihe Road, Hefei, 230031, P.R,China
My name is Enyuan Pan- I am from Department of Pharmacy, Anhui University of Traditional Chinese Medicine, Shihe Road, Hefei, 230031, P.R,China My area of interests are Rheumatoid arthritis
Research Article Open Access
Author(s): Youjun Zhou, Shuangying Gui, Jian Wang, Shanshan Qian and Enyuan Pan
Therapeutic Effects of Sinomenine Microemulsion- Based Hydrogel on Adjuvant-Induced Arthritis in Rats
Sinomenine is an alkaloid isolated from the traditional Chinese medicinal herb Sinomenium acutum, which has been used for the treatment of rheumatoid arthritis in China. The objective of this work was to investigate the effect of sinomenine microemulsion-based hydrogel (SMBH) on Freund’s complete adjuvant-induced arthritis(AA) in Wistar rats. The SMBH was formulated as follows: 4%sinomenine, 2% oleic acid, 16.7% Tween-20, 41% distilled water,33.3% absolute alcohol, 3% menthol, and 2% carbomer (w/w).Treatment was started on the seventh day after AA was induced. All ... view moreĀ»