Erkan Vuralkan Author

Research Article Open Access

May Hyperbaric Oxygen Therapy Play a Role in the Treatment of Allergic Rhinitis? A Double- Blind Experimental Study in Rat Model Hyperbaric Oxygen Therapy on Allergic Rhinitis

Author(s):

Erkan Vuralkan, Hatice Bengu Cobanoglu1, Bengusu Mirasoglu, Sevdegul Mungan, Abdullah Arslan, Bekir Selim Bagli, Akın Savas Toklu and Inan Utku Türkmen

Objectives: Medical treatments may be inadequate for the management of allergic rhinitis. Therefore, it requires different treatment options. We aimed to evaluate the effects of nasal steroid and hyperbaric oxygen (HBO) treatments on the nasal mucosa of an allergic rhinitis of a (AR) rat model.

Methods: Group 1 (control group); Group 2 toluene diisocyanate (TDI) group; Group 3 was exposed to TDI and treated with HBO; Group 4 was exposed to TDI and treated with intranasal
mometasone furoate. After the sacrification, the sections were then evaluated semi-quantitatively and parameters of histopathological inflammation, fibrosis and eosinophilia were assessed.

Results: The level of inflammation in the control group ... view more»

DOI: 10.4172/2324-8785.1000335

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