Fariba Fathirad Author

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In Situ Preparation of Magnetic Fe₃ O₄ Nanoparticles in Presence of PLGA and PVA as Magnetite Nanocarrier for Targeted Drug Delivery

Author(s):

Mitra Ghanbari, Tayebeh Shamspur and Fariba Fathirad

Introduction: Drug targeting represents an interesting motivation to prevent side effects and increase doxorubicin cytotoxicity. Magnetic nanoparticles offer new opportunities for developing effective drug delivery systems because they are feasible to produce characterize and specifically tailor their functional properties for drug delivery applications. To improve their stability and biocompatibility, the Fe3O4 nanoparticles are often modified with surfactants or polymers.

Materials and Methods: In the present work, a nanocomposite was synthesized via in situ preparation of Fe3 O4 nanoparticles inside poly lactic glycolic acid and poly vinyl alcohol. The anticancer drug of doxorubicin was loaded on the synthesized nanocomposite in order to tar... view more»

DOI: 10.4172/2325-9604.1000167

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