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Guido Bonomo Author
Subjects of specialization
Affiliation
Metastatic melanoma; Liver metastasis; Whole organ therapy; Percutaneous hepatic perfusion
Division of Hematology, European Institute of Oncology IRCCS, Milan, Italy
Biography
Dr. Guido Bonomo is worling in the Division of Hematology, European Institute of Oncology IRCCS, Milan, Italy and having specialization in the field of Metastatic melanoma; Liver metastasis; Whole organ therapy; Percutaneous hepatic perfusion
Publications
Case Report Subscription
Hepatic Chemoperfusion: A Comparison between Old and New Generation Filters in Patients Affected by Liver Metastasis from Melanoma
Author(s): Pier Francesco Ferrucci, Emilia Cocorocchio, Paolo della Vigna, Guido Bonomo and Franco Orsi
Despite immunotherapy and targeted therapies, have significantly improved patients expectations, effective approach to non-resect able liver metastatic melanomas remains a major challenge in interdisciplinary oncology. Patients with liver metastases usually die of their disease, mostly due to acquired resistances to systemic drugs and to persistence of micro-metastatic clones.
Recently, whole organ-focused strategies had been proposed in order to extend patient’s benefits addressing those complains. In particular, liver chemoperfusion with Delcath CHEMOSAT® product (CS-HDS) is designed to perfuse the entire liver with a chemotherapeutic agent (melphalan hydrochloride), with simultaneous extra-corporeal filtration of the hepatic venous blood, in order to re... view more»
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