Horaacute;cio Scigliano Silva Author
Subjects of specialization
Affiliation
cancer, cancer oncology, Carcinogenesis
Pathological Anatomy Service, Centro Hospitalar de Entre o Douro e Vouga, EPE, S
Dr. Horaacute;cio Scigliano Silva is working as scientist and professor at Pathological Anatomy Service, Centro Hospitalar de Entre o Douro e Vouga, EPE, São Sebastião Hospital, Portugal. The author has specalization in cancer, cancer oncology, chemotherapy, Carcinogenesis, Chemotherapy
Case Report Open Access
Author(s): Aurea Lima, Alcinda Reis, Horácio Scigliano Silva, Manuela Machado, Ana Luísa Faria and Amanda Nobre
Ectopic secretion of β-hCG by lung cancer is rare, particularly regarding male patients. Here we describe a clinical case of a β-hCG-secreting lung squamous cell carcinoma who had an exceptional response to 3rd line therapy nivolumab.
A 52-year-old man, KPS score of 90, presented a 12-month history of intermittent right-sided testicular pain. No other positive findings were issued in the anamnesis and/or at physical examination. Despite β-hCG serum elevation, no other changes were observed on analytical studies. No abnormalities were described on scrotal ultrasonography. CT showed thoracic lymphadenopathies and a right adrenal gland mass. PET/CT showed abnormal FDG uptake in the referred lymphadenopathies and mass. EBUS-TBNA biopsy and pathology examination reve... view more»