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Hindi Journal of Liver: Disease & TransplantationISSN: 2325-9612
Irene Oi Lin Ng Author
Subjects of specialization
Affiliation
Pathology, Molecular basis in the formation and progression of liver cancer, Identification of liver cancer stem cells, Characterization of important genes, Cell signaling pathways and microRNAs
State Key Laboratory for Liver Research, Li Ka Shing Faculty of Medicine at The University of Hong Kong, Hong Kong.
Biography
Professor Irene Ng is currently the Chair Professor of Department of Pathology in the University of Hong Kong.She is also the Director of the State Key Laboratory of Liver Research. Professor Ng graduated with an M.B.B.S. degree from the University of Hong Kong.Her laboratory looks into the major oncogenic signaling pathways in liver cancer and their co-operation and crosstalk. Significantly, she has established useful pathological and biological parameters with prognostic significance for patient management.
Publications
Editorial Open Access
Revisiting the Role of TLR/IRAK Signaling and its Therapeutic Potential in Cancer
Author(s): Bowie Yik Ling Cheng, Irene Oi Lin Ng, and Terence Kin-Wah Lee
Interleukin-1 receptor-associated kinase (IRAK) family consistsof four members: IRAK1, IRAK2, IRAK3/M and IRAK4. They are key downstream mediators of toll-like receptor (TLR) and interleukin-1 receptor (IL1R) pathways.In particular, TLR, a family of transmembrane pattern recognition receptor (PRR), play a crucial role in the induction of innate and adaptive immune responds against microbial infection, tissue injury and also cancer.
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