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Hindi Cell Biology: Research & TherapyISSN: 2324-9293
James E Verdone Author
Subjects of specialization
Affiliation
Cellular Immunology,Cellular Pathology,Cell Tissue Studies,Cell Regeneration,Cell therapy
The James Buchanan Brady Urological Institute and Department of Urology
Biography
James E Verdone is currently working in Department of Medical Biochemistry at University of Aarhus, Denmark. He has international experience on various programs, and also contributed and participated in different countries for diverse fields of study. Research interests reflect in wide range of publications in various national and international journals.
Publications
Short Communication Subscription
Chemotherapy Increases Aggressiveness of Prostate Cancer via Epithelial Mesenchymal Transition
Author(s): John J Kim, James E Verdone and Steven M Mooney
Chemotherapy Increases Aggressiveness of Prostate Cancer via Epithelial Mesenchymal Transition
Although chemotherapy has been used as a major therapeutic weapon against advanced prostate cancer, overcoming drug resistance is still a major challenge. Cancer has been known to diminish therapeutic effect by several molecular mechanisms– increasing efflux by recruiting cell membrane pumps and limiting drug diffusion by constructing leaky vasculature. Moreover, recent studies suggest that long-term treatment with chemotherapy may have detrimental effects for patients presenting with solid tumors. Specifically, prostate cancer epithelial cells develop resistance t... view more»
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