Journal of Virology & Antiviral ResearchISSN: 2324-8955

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Jennifer A Thompson Author

Jennier.A@virginia.edu

Subjects of specialization
Virus Replication, Endoplasmic Reticulum

Affiliation
Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, Virginia 22908, USA

Biography

Jennifer a Thompson affiliated to the Department of Microbiology, Immunology, and Cancer Biology at University of Virginia Health System, USA. Her current research interests include in Virus Replication, Endoplasmic Reticulum.

Publications

Review Article Subscription

Role of Coatomer Protein I in Virus Replication

Author(s): Jennifer A Thompson and Jay C Brown

Role of Coatomer Protein I in Virus Replication

Coatomer protein I (COPI) is well known as the protein coat surrounding vesicles involved in returning endoplasmic reticulum (ER)-resident proteins to the ER. COPI coats are also found in vesicles involved in other trafficking processes including endocytosis, autophagy and anterograde transport in the secretory pathway. In view of the diverse functions of COPI proteins, it is expected that they will affect virus replication, and many reports of such COPI involvement have now appeared. The experimental approaches most often employ specific siRNA to deplete COPI subunits or brefeldin A to block COPI activation.

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DOI: 10.4172/2324-8955.1000102

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