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Hindi Endocrinology & Diabetes ResearchISSN: 2470-7570
Jianting Li Author
Subjects of specialization
Affiliation
Sciences, Microbiology
Institute of Microbiology Chinese Academy of Sciences, Institute of Process Engineering Chinese Academy of
Biography
| Institute of Microbiology Chinese Academy of Sciences, Institute of Process Engineering Chinese Academy of Sciences, Shandong University, Shanghai Jiao Tong University, University of Maryland at College Park, University of Texas at Austin |
Publications
Review Article Subscription
The Interaction between Metformin and Bile Acids in Metabolic Disease
Author(s): Jianting Li, Yang Liu and Shuguang Pang
Objective: To review the function of bile acids and the mechanism of metformin in lipid and glucose metabolism, and the interaction between metformin and bile acids.
Methods: PubMed and Google Scholar were searched using terms such as bile acid, lipid, glucose, metformin and type 2 diabetes. Additional relevant references were identified by reviewing the reference lists of articles.
Results: Bile acids are important molecules of regulating glucose and lipid metabolism through FXR and TGR5, while metformin through AMPK signaling pathway. Regulator role of metformin in glucose and lipid metabolism might be associated with bile acid metabolism.
Conclusions: Metformin as a welcomed antidiabetic dru... view more»
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