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Hindi International Journal of Ophthalmic PathologyISSN: 2324-8599
Kazuo Tsubota Author
Subjects of specialization
Affiliation
Corneal Regeneration, Dry Eye
Department of Ophthalmology, Keio University School of Medicine, Japan
Biography
Kazuo Tsubota is professor emeritus of the Department of Ophthalmology at Keio University School of Medicine. An internationally recognized dry eye specialist, Prof. Tsubota has been working on the pathogenesis and treatment of dry eye for much of his career. He was the first Japanese recipient of the American Academy of Ophthalmology Honor Award and is author of more than 700 scientific peer-reviewed articles.
Publications
Research Article Open Access
A fatal case of acute bilateral orbital apex syndrome with mucormycosis
Author(s): Hiromitsu Kunimi, Yusaku Katada*, Masaki Fukui, Shinji Ideta, Ohde Hisao, Kazuo Tsubota
We report a fatal case of mucormycosis that started with an acute bilateral orbital apex syndrome. A 44-year-old man with severe alcoholic hepatitis visited our hospital with a chief complaint of sudden visual loss in his left eye. The cranial computed tomography scan and magnetic resonance imaging revealed a lesion in his left orbital apex. After being diagnosed with orbital apex syndrome due to infection, he was prescribed antibiotic and antifungal therapy. Despite the treatment, he showed no improvement, and he lost vision in the contralateral eye. He also developed cranial nerve symptoms. His general condition worsened rapidly; within a week, he died of multiple organ failure. Pathologic examination confirmed the diagnosis of invasive mucormycosis.
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