Konda Mani Saravanan Author
Subjects of specialization
Affiliation
Bioinformatics, Biophysics, Structural Biology, Peptide and Protein Engineering, Protein Science
Department of Bioinfomatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, China
Dr. Saravanan has received his Ph.D. Bioinformatics on inter residue interactions in protein structures from Bharathidasan University under the supervision of Dr. S. Selvaraj and he has taken his Post-doctoral fellowship under the distinguished UGC Dr DS Kothari and he worked as a Proffesor in S. Krishnaswamy’s research group at Madurai Kamaraj University. Dr. Saravanan got the University First Rank, Gold medal in M.Sc. Bioinformatics.
Research Article Subscription
Author(s): Konda Mani Saravanan
Sequence Analysis of Holins by Reduced Amino Acid Alphabet Model and Permutation Approaches
Objective: Holins are small proteins which perform many important functions in the cytoplasmic membrane of the cell. There is no crystal structure of holins reported in Protein Data Bank and hence computational sequence analysis is the only alternative to understand structure and functional consequences of these proteins. In the present work, we engaged several careful computational procedures to explore the important amino acid residues responsible for functioning of holins on membranes. Methods: To explore r... view moreĀ»