Larysa B Bondarenko | Author | SciTechnol

Larysa B Bondarenko Author

anna_shayakhmetova@yahoo.com +380444567866

Subjects of specialization
working imnDepartment, SI Institute of Pharmacology

Affiliation
Department, SI Institute of Pharmacology & Toxicology of National Academy of Medical Sciences of Ukraine, Eugene Pottier 14, Kyiv, 03680, Ukraine,

Biography

Toxicology of National Academy of Medical Sciences of Ukraine, Eugene Pottier 14, Kyiv, 03680, Ukraine Isoniazid is reported to be the most reliable and cost-effective remedy for tuberculosis treatment and prophylaxis among first line anti-tuberculosis drugs. Conventionally, the most common and best studied adverse effect of isoniazid is hepatotoxicity, but as for testicular

Publications

Review Article Subscription

Cytochrome P4502E1 and Other Xenobiotics Metabolizing Isoforms in Pathogenesis of Male Reproductive Disorders

Author(s):

Ganna M Shayakhmetova and Larysa B Bondarenko

Cytochrome P4502E1 and Other Xenobiotics Metabolizing Isoforms in Pathogenesis of Male Reproductive Disorders

Last decades investigations demonstrated significant decreasing of men fertility and sperm quality. Approximately, 50% clinically confirmed infertility cases are attributed to the male partners. Male infertility pathogenesis is investigated insufficiently; its direct interrelation with such pathologies as varicocele or urogenital infections was demonstrated only in 23% of cases. At present, it is supposed that different etiologic factors (including idiopathic) could start similar processes, which final result would be spermatozoids quality, and/or quantity decreasi... view more»

DOI: 10.4172/2324-8793.1000108

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