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Hindi Clinical Oncology: Case Reports
Laura Goff Author
Subjects of specialization
Affiliation
Gastrointestinal Cancer,Medicine: ,Hematology ,Oncology
Associate Professor of Medicine (Hematology/Oncology) Executive Medical Director for the VICC Cancer Patient Care Center, Co-Chair, Data and Safety Monitoring Committee"
Biography
Dr. Laura Goff is an Associate Professor of Medicine (Hematology/Oncology) Executive Medical Director for the VICC Cancer Patient Care Center Co-Chair,and Data and Safety Monitoring Committee
Publications
Case Report Open Access
Brachytherapy Boost to Tumor Bed Prior to Adjuvant Chemoradiation in Margin Positive Resected Cholangiocarcinoma
Author(s): Satya Das*, John Kelly Wrigh, Laura Goff, Anuradha Chakravarthy and Emily Chan (USA)
Importance: The role of adjuvant therapy in resected cholangiocarcinoma patients is unproven despite poor survival rates even in completely resected patients. Most relapses occur locally and within a relatively short window from time of resection. R1 resection and lymph node positive patients are particularly at high risk for local relapse. Observation: Adjuvant modalities have not been compared head to head against one another in cholangiocarcinoma patients. The recent phase III PRODIGE 12-ACCORD 18 trial assessing adjuvant chemotherapy with gemcitabine and oxaliplatin in this group of patients was a negative study. Adjuvant radiation has been shown in some retrospective series to improve overall survival in R1 resected and lymph node positive patients. Other retrospective studies sugg... view more»