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Hindi Clinical Oncology: Case Reports
Lawrence Sevilla Parwanand Sajin M Karakattu Author
Subjects of specialization
Affiliation
cancer, cancer oncology, Carcinogenesis
Department of Internal Medicine, East Tennessee State University, Johnson City, USA Department of Critical Care, East Tennessee State University, Johnson City, USA
Biography
Dr. Lawrence Sevilla Parwan is working as scientist and professor at Department of Internal Medicine, East Tennessee State University, Johnson City, USA and Dr. Sajin M Karakattu is working as scientist and professor at Department of Critical Care, East Tennessee State University, Johnson City, USA. The author has specalization in cancer, cancer oncology, chemotherapy, Carcinogenesis, Chemotherapy
Publications
Case Report Subscription
Pembrolizumab Associated Pericardial Effusion In A Patient With Advanced Esophageal Cancer
Author(s): Akesh Thomas, Emmitt Lee Turner, Lawrence Sevilla Parwan and Sajin M Karakattu
Pembrolizumab is an Immune Checkpoint Inhibitor (ICI) that exerts anti-tumor activity by inhibiting the interaction of programmed cell death protein 1 with its ligand (PD-L1) on activated lymphocytes.Immune Related adverse effects are a major concern for the use of ICI. We are reporting the case of a 64 year old white male with advanced esophageal adenocarcinoma who presented with moderate pericardial effusion after receiving treatment with pembrolizumab. The patient was treated with systemic steroids which improved his condition. Clinicians should consider the possibility of Immure related adverse effects in patients receiving immunotherapy with a wide array of presentations.
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