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Hindi Clinical Dermatology Research JournalISSN: 2576-1439
Leelavathy Budamakuntla Author
Subjects of specialization
Affiliation
Medical cosmetology, Autoantibodies, Hyperpigmentation, Biological Therapy, Skin
Department of Dermatology, Bowring and Lady Curzon Hospital and Research Institute Bangalore Medical College and Research Institute, Bangalore, India
Biography
Leelavathy Budamakuntla is affiliated with the Department of Dermatology, Bowring, and Lady Curzon Hospital and Research Institute Bangalore Medical College and Research Institute, Bangalore, India. having the skills and expertise of medical cosmetology, autoantibodies, hyperpigmentation, biological therapy, and skin.
Publications
Research Article Open Access
IL 17 Cytokine in Psoriasis: Before and After Methotrexate and NBUVB Phototherapy: A Longitudinal Study
Author(s): Leelavathy Budamakuntla, Eswari Loganathan, Pavithra Gundappa, Sreelakshmi and Tapasya Kini and Kavya K
Background: Psoriasis, a disease of abnormal epidermal proliferation, was found to be T helper-1 disease. Currently a new concept of T Helper 17 has been found to play a major role through
IL-17 and IL-22 cytokines in the disease pathogenesis.
Aim: Since IL 17 is one of the key effector cytokine of Th17 pathway, we conducted a 12 week longitudinal study of effect of NBUVB phototherapy and Methotrexate on serum IL 17 levels in patients with psoriasis before and after treatment.
Materials and Methods: This was a prospective longitudinal study done on 28 psoriasis patients with PASI>10 and 10 controls. Serum IL-17 levels and PASI scoring was estimated at baseline and after 12 weeks after t... view more»
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