Manuel G Ramirez Author
Subjects of specialization
Affiliation
Pharmacoepidemiology
Baxter Healthcare Corp. Associate Director, Global HEOR Advanced Surgery, USA
I am Manuel G Ramirez, belonging to the Unit of Pharmacoepidemiology & Pharmacoeconomics, interested in the field of Pharmacoepidemiology & Pharmacoeconomics, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
Review Article Open Access
Author(s): Nitin Khanna, Manuel G Ramirez and Mark P Connolly
Studies have repeatedly demonstrated the importance of hemostasis in surgery which is essential for promoting positive outcomes and conserving healthcare resources. The need to minimize blood loss is also necessary for achieving good visibility of the operative site and preventing adverse physiological events associated with blood loss. To improve surgical outcomes hemostatic agents, including surgical sealants, have been used to achieve hemostasis in a wide range of specialties including orthopedics, traumatology, urology, neurosurgery, otorhinolaryngology, and gynecology. One of the early commercial products FloSeal for managing hemostasis overcame the limitations of earlier topical hemostatic agents, namely variable efficacy and lack of efficacy in heparinized patients, by comb... view moreĀ»