Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi Journal of Nanomaterials & Molecular NanotechnologyISSN: 2324-8777
Masazumi Eriguchi Author
Subjects of specialization
Affiliation
Life and Environmental Sciences.
Japan Anti-tuberculosis Association, Shin-Yamanote Hospital, Clinical Medical- Engineering Laboratory, 3-6-1 Suwa-cho, Higashimurayama, Tokyo 189-0021, Japan
Biography
Masazumi Eriguchi working at the japan Anti-tuberculosis Association, Shin-Yamanote Hospital, Clinical Medical- Engineering Laboratory, Higashimurayama, Tokyo, Japan. Masazumi Eriguchi has an area of research interest in the field of Life and Environmental Sciences.
Publications
Research Article Open Access
Effect of pDNA Complex Particle Size on Gene Expression: Difference between In Vitro and In Vivo Experiments
Author(s): Tomoko Ito, Masazumi Eriguchi and Yoshiyuki Koyama
Effect of pDNA Complex Particle Size on Gene Expression: Difference between In Vitro and In Vivo Experiments
We have developed a novel gene-transfection system comprising very small (70-150 nm) plasmid/polyethyleneimine/hyaluronan (HA) ternary complexes having negative surface charge, and reduced nonspecific interactions with bio-components. They showed high in vivo gene expression efficiency. However, in in vitro transfection experiments, such small ternary complexes often demonstrated rather much lower gene expression than the conventional DNA/ polycation complex. In this study, we investigated the influence of the complex particle size on gene expr... view more»
Google Scholars / Researchers Sites
