Mirza Masroor Ali Beg Author

Editorial Open Access

Radiology 2018: Clinical importance of circulating EGFR mRNA expression in non-small cell lung cancer patients- Mirza Masroor Ali Beg- Maulana Azad Medical College

Author(s):

Mirza Masroor Ali Beg

Background: Non-Small Cell Lung Cancer (NSCLC) is a disease involving uncontrolled cell growth, which could result in metastases into nearby tissues beyond the lungs. The molecular mechanisms involved in NSCLC are still relatively unknown and are being investigated extensively. Materials & Method: Present study aimed to analyze the importance of Epidermal Growth Factor Receptor (EGFR) gene expression on metastasis and survival in Indian NSCLC patients. The present case-control study included 100 cases of NSCLC patients and 100 age- and sex-matched controls. EGFR gene expression was analyzed by quantitative real time PCR using serum RNA. Association with NSCLC patient survival was analyzed by the Kaplan-Meier method. Result: We analyzed circulating EGFR gene expression and observed m... view more»

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