Mohamed Ismail Seleem Author
Subjects of specialization
Affiliation
Hepatobiliary Surgery, Hepatology, Liver Transplantation, Hepatocellular Carcinoma, Hepatopancreatobilliary Surgery
Head of Hepato-Pancreatico-Biliary Surgery Department, National Hepatology and Tropical Research Institute, Egypt
Review Article Subscription
Author(s): Mohamed Ismail Seleem, Ahmed Elewa
Liver transplantation, whether from a deceased or living donor (LDLT), is still a definite line of treatment for decompensated cirrhosis, early stage of hepatocellular carcinoma, and acute liver failure. Organs from living donors offer many potential advantages over organs from deceased donors; the most important is the optimization of the timing of transplantation. Also preservation time is minimal, so there is significantly less ischemic damage. Time-zero biopsies sampled after graft revascularization predicts adverse clinical outcomes after liver transplantation. It is well known that severe Ischemia/reperfusion injury (IRI) signals the likely need for early retransplantation. This fact emphasizes the value of the time –zero biopsy sampled immediate... view moreĀ»