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Hindi Journal of Nanomaterials & Molecular NanotechnologyISSN: 2324-8777
Murugesan R Author
Subjects of specialization
Affiliation
Signal, Image and Video Processing, Bioinformatics, Cancer Research, Cancer Biology, PCR
Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Kelambakkam, Chennai, Tamilnadu, India
Biography
Facile Synthesis of Zinc Alloyed Cadmium Selenide (Cd/ZnSe) Quantum Dots and its Photocatalytic Activity and In Vivo Toxicity Assessment in Danio rerio Embryos is one of the main research works of Ramachandran Murugesan. Ramachandran Murugesan is from Chettinad Academy of Research and Education, Kelambakkam, Chennai, Tamilnadu, India.
Publications
Research Article Subscription
Chitosan Nanoparticles as a Potential Drug Delivery System for Photodynamic Therapy of Cancer
Author(s): Amsaveni G, Sakthivel M, Kathiravan K, Anish B and Murugesan R
Objective: Chitosan nanoparticles (CS-NP) can imbibe water insoluble anticancer agents into its hydrophobic multicores. In the present study, chitosan nanoparticles, a nanoscale drug carrier system is investigated for its potential as a drug delivery system for porphyrin based photodynamic therapy. Methods: Zinc meso tetra phenyl porphyrin (ZnmTPP) encapsulated CS-NP was prepared by ionic gelation method. The synthesized nanoparticles were characterized using dynamic light scattering studies, zeta potential analysis and AFM analysis. Results: Freshly prepared chitosan nanoparticles had an average hydrodynamic diameter of 175 nm and are nearly spherical in shape as per light scattering measurements and atomic force imaging respectively. As nanoscale drug carriers, (ZnmTPP) encapsulated c... view more»
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