Journal of Clinical & Experimental OncologyISSN: 2324-9110

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Mustafa BA Djamgoz Author

m.djamgoz@imperial.ac.uk 44 (0) 207 594 5370

Subjects of specialization
Mucoepidermoid carcinoma, Cancer chemotherapy, Prostate biomarker

Affiliation
Neuroscience Solutions to Cancer Research Group, Department of Life Sciences, Imperial College London, South Kensington Campus, London SW7 2AZ, UK

Biography

Mustafa BA Djamgoz was working in the Neuroscience Solutions to Cancer Research Group, Department of Life Sciences, Imperial College London, South Kensington Campus, London SW7 2AZ, UK. Doctor has more than 40 publications. Doctor's current research area related to Clinical Oncology.

Publications

Review Article Subscription

Biophysics of Cancer: Cellular Excitability (“CELEX”) Hypothesis of Metastasis

Author(s): Mustafa BA Djamgoz

Biophysics of Cancer: Cellular Excitability (“CELEX”) Hypothesis of Metastasis

This article advances a novel hypothesis of metastasis called “CELEX” (for cellular excitability) and presents the current evidence for it. The CELEX hypothesis is based upon concerted expression of voltage-gated ion, particularly Na+ and K+, channels during cancer progression. Electrophysiological recordings from human carcinoma cell lines have shown that, unlike weakly/nonmetastatic cells, cells that have strong metastatic potential express voltage-gated Na+ channels and much reduced outward, mainly K+ currents. Furthermore, the Na+ channel expression is selfsustaining by acti... view more»

DOI: 10.4172/2324-9110.S1-005

Abstract HTML PDF

Google Scholars / Researchers Sites

Explore SciTechnol

GET THE APP