Nasim Raad Author
Subjects of specialization
Affiliation
Ecchymosis, Hemorrhage, Edema, Rhinoplasty, Tranexamic acid
Tracheal Diseases Research Center, Department of Otolaryngology Head and Neck Surgery, National Research Shahid Beheshti University of Medical Sciences, Tehran, Iran
Nasim Raad, belonging to Tracheal Diseases Research Center, Department of Otolaryngology Head and Neck Surgery, interested in the field of Ecchymosis from National Research Institute of Tuberculosis and Lung Diseases, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Research Article Open Access
Author(s): Jahangir Ghorbani, Shideh Dabir, Sara Roudgari and Nasim Raad
Background: Intraoperative bleeding and postoperative periorbital edema and ecchymosis are the main concerns in septorhinoplasty surgery. Tranexamic acid, an antifibrinolytic agent, is used to reduce bleeding in nasal surgeries. The aim of this prospective double blind, randomized, controlled study was to assess the efficacy of a prophylactic low dose of tranexamic acid on bleeding and periorbital edema and ecchymosis in open septorhinoplasty. Methods: 52 American Society of Anesthesiologists class I adult patients scheduled for open septorhinoplasty under total intravenous anesthesia were randomized into 3 groups to receive either a bolus dose of 500 mg oral or intravenous tranexamic acid or placebo prior to the surgery. Results: There were no significant differences in the intraoperat... view moreĀ»