Nermeen E Shaffie | Author | SciTechnol

Nermeen E Shaffie Author

Subjects of specialization
Clinical Pathology,Cellular Pathology,Cell Tissue Studies,treatment of diseases,Cell Motility

Affiliation
Clinical Pathology Department, NRC, Cairo, Egypt

Biography

Nermeen E Shaffie is currently working in Clinical Pathology Department, NRC, Cairo, Egypt. He has international experience on various programs, and also contributed and participated in different countries for diverse fields of study. Research interests reflect in wide range of publications in various national and international journals.

Publications

Research Article Subscription

Cannabis resin extract in Parkinson's disease: Behavioral, Neurochemical, and Histological Evaluation

Author(s):

Shaimaa A ElShebiney, Ezzeddein S El-Denshary, Omar ME Abdel-Salam, Neveen A Salem, Zakaria A El-Khyat, Nermeen E Shaffie and Dalaal M Abdallah

Cannabis sativa (Family Cannabaceae, L.) has been used in China and India for thousands of years as a medicine. The main active constituents of cannabis are Δ 9 -tetrahydrocannabinol (THC), cannabinol (CBN) and cannabidiol (CBD). Currently, THC and CBD are being carefully used in conditions, such as multiple sclerosis, cancer pain, and chemotherapy associated emesis. The cannabinoid 1 receptor (CB1R) is considered responsible for most THC effects involving sedation, analgesia, hypothermia, catalepsy, and euphoria . CB1Rs are abundantly distributed in the basal ganglia , where they are co-localized with both dopamine (D)1 and 2 receptors on striatonigral dynorphin/substance P and striatopallidal enkephalinergi... view more»

DOI: 10.4172/2324-9293.1000112

Abstract HTML PDF