Journal of Nanomaterials & Molecular NanotechnologyISSN: 2324-8777

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Neubert HHR Author

tsige.gmariam@aau.edu.et

Subjects of specialization
Nanoscience, Nanotubes, Nanomaterials, Nanotechnology, Nanoparticles.

Affiliation
Institute of Applied Dermatopharmacy, Martin Luther University, Halle-Wittenberg, Germany

Biography

Fabrication and Evaluation of Cassava Starch Acetate Nanoparticles Loaded with Drugs of Various BCS Classes: Influence of Drug Solubility and Partition Coefficient is one of the research works of Neubert. Neubert is in the Institute of Applied Dermatopharmacy, Martin Luther University, Halle-Wittenberg, Germany.

Publications

Research Article Subscription

Fabrication and Evaluation of Cassava Starch Acetate Nanoparticles Loaded with Drugs of Various BCS Classes: Influence of Drug Solubility and Partition Coefficient

Author(s):

Getahun Paulos, Gebre-Mariam T and Neubert HHR

A successful fabrication of nanocarrier for drug delivery should yield nanoparticles (NPs) with suitable particle size and size distribution and provide high drug-loading capacity. Factors that influence these attributes include physicochemical properties of the drug, the nature of the nanocarrier, and processing variables, among others. The aim of this study was, therefore, to investigate the influence of solubility and partition coefficient of different drugs on the characteristics of starch-based NPs. Cassava starch was chemically modified by acetylation, at different degrees of substitution (DS) and characterized. The starch acetates (SAs) were then used for the preparation of drug-loaded NPs. Different model drugs: ibuprofen (BCS class II), acyclovir (B... view more»

Abstract HTML PDF

Social Media

Google Scholars / Researchers Sites

Explore SciTechnol

GET THE APP