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Hindi Clinical Oncology: Case Reports
Nicole Bernd Becker Author
Subjects of specialization
Affiliation
cancer, cancer oncology, Carcinogenesis
School of Medicine, Pontifical Catholic University of Rio Grande do Sul, Brasil
Biography
Dr. Nicole Bernd Becker is working as scientist and professor at School of Medicine, Pontifical Catholic University of Rio Grande do Sul, Brasil. The author has specalization in cancer, cancer oncology, chemotherapy, Carcinogenesis, Chemotherapy
Publications
Case Report Open Access
Challenging Radical Nephrectomy after Treatment with Nivolumab
Author(s): Fernanda Nascimento Lubianca, Nicole Bernd Becker, Aline Petracco Petzold, Carolina Knorst Kepler, Carolina de Mello Viera, Laura Gazal Passos, Rafael Nazário Bringhenti, André P Fay and Gustavo Franco Carvalhal
Advanced Renal Cell Carcinoma (RCC) is a lethal urologic neoplasm. In cases of local progression and symptoms or in the case of a complete or significant response in the metastatic sites after systemic therapies, Cytoreductive Nephrectomy (CN) is selectively considered. Recently, it has been suggested that the use of Immune Checkpoint Inhibitors (ICIs) prior to CN could be associated with increased fibrosis and adhesions in and around the affected kidney, although the literature is scarce and controversial in this regard. Some authors postulate that the induction of the inflammatory reaction caused by ICIs on the tumours may result in significant perioperative morbidity. Aiming to contribute to the elucidation of this matter, we report a case in which nivolumab was used prior to a diffi... view more»
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