Ortega-Alb?s JJ Author
Subjects of specialization
Affiliation
Sleep disorders, Psychiatry-Personality Disorders, Sleep
Department of sleep medicine, Sleep Unit Universitary, General Hospital of Castell
Juan José Ortega Albás is Somnologist expert in Sleep Medicine, accredited by European Sleep Research Society (ESRS) and Spanish Comitee (CEAMS). He is Chief of Sleep Unit, Universitary General Hospital of Castellón (Spain) & Vice-president of the Sleep Spanish Society. More than forty published papers in journals of high impact factor (Sleep Medicine, Neurology, European Neurology, Sleep and Breathing, Journal of Neuropsychiatry and clinical Neuroscience…).
Commentary Subscription
Author(s): Ortega-Alb?s JJ and Ortega Gab?s SP
Sodium Oxibate and Breathing
The gamma-hydroxybutyrate acid (GHB) is a short chain fatty acid, an endogenous metabolite of gamma–aminobutyric acid (GABA), known major inhibitor neurotransmitter. The GHB presents an action fundamentally at Central Nervous System (CNS) level, and possesses a high affinity for specific receptors located in the cerebral cortex and in the medulla. Sodium Oxybate (SO) is the sodium salt of the GHB. Its character as inhibitor neuromodulator, with the possibility of inducing respiratory depression, and the potential risk of abuse/misuse forces clinicians to be consta... view moreĀ»