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Hindi International Journal of Ophthalmic PathologyISSN: 2324-8599
Paolo Brusini Author
Subjects of specialization
Affiliation
Glaucoma, Cataract Phacoemulsification, Lamellar Corneal Surgery
Department of Ophthalmology, Azienda Ospedaliero-Universitaria S. Maria della Misericordia, Udine, Italy
Biography
Dr. Paolo Brusini is specialized in ophthalmology at the University of Messina. He was head of the Ophthalmic Unit at the Hospital of San Donà di Piave, Chief of the Department of Ophthalmology at Santa Maria della Misericordia Hospital and Città di Udine” Health Center and founder and president of the Italian Society of Perimetry. He is a member of numerous international professional societies. He was a guest speaker at lectures and invited presentations in more than 200 national and international congresses and conferences in various fields of Ophthalmology and conducted more than 350 clinical courses.
Publications
Research Article Subscription
Cultured Human Keratocytes from the Limbus and Cornea Both Express Epithelial Cytokeratin 3: Possible Mesenchymal-Epithelial Transition
Author(s): Giuseppina Perrella, Cathryn Anne Scott, Renza Spelat, Paolo Brusini, Federica D?Aurizio, Ilaria De Pol and Harminder Singh Dua
The corneal limbus is the repository of epithelial stem cells (SC) that sustain the turnover of corneal epithelial cells. The limbus stroma contains mesenchymal SC that generates stromal keratocytes. Mesenchymal-epithelial transition is a phenomenon wherein cells of mesenchymal phenotype can transdifferentiate to epithelial phenotype. Our aim was to study whether limbal keratocytes, cytokeratin 3 (CK3) negative, could be induced to transdifferentiate into CK3 positive cells.
Human keratocytes were isolated from the limbus and cornea of cadaver donors, cultured and evaluated for CD3... view more»
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