Clinical Oncology: Case Reports

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Poornima Ramadasand David B Duggan Author

pra003@lsuhs.edu

Subjects of specialization
cancer, cancer oncology, Carcinogenesis

Affiliation
LSU Health Sciences Center, 1501 Kings Hwy, Shreveport, Louisiana, USA

Biography

Dr. Poornima Ramadas is working as scientist and professor at LSU Health Sciences Center, 1501 Kings Hwy, Shreveport, Louisiana, USA. The author has specalization in cancer, cancer oncology, chemotherapy, Carcinogenesis, Chemotherapy

Publications

Case Report Open Access

Complete Remission of Acute Myeloid Leukemia in an Elderly Patient with a Single Dose of Venetoclax

Author(s):

Poornima Ramadas and David B Duggan

Treatment of Acute Myeloid Leukemia in older adults becomes challenging due to co-morbidities, poor functional status, higher incidence of unfavorable cytogenetics, and increased treatment resistance. Even though the overall survival in older patients with AML has historically remained poor, recent advances in treatment have resulted in improved survival in this population. Venetoclax, an oral BCL-2 inhibitor in combination with hypomethylating agents or low-dose cytarabine has been granted FDA approval for treatment of AML in patients who are 75 years or older or have co-morbid conditions that prohibit the use of intensive chemotherapy. This case report describes an elderly male patient who was diagnosed with AML and went into complete remission with a single dose of Venetoclax. Older ... view more»

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