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Hindi Journal of Pharmaceutical Sciences & Emerging DrugsISSN: 2380-9477
Prerna Author
Subjects of specialization
Affiliation
Pharmacology, Pharmaceutical Sciences, Medicinal Chemistry, Drag reduction, Drug Therapy
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125001, Haryana, India.
Biography
Prerna; Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125001, Haryana, India. She stated that, "The synthesized okra, alginate composite beads were characterized by fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy."
Publications
Research Article Subscription
Preparation Optimization and Evaluation of Okra Mucilage Sodium Alginate Mucoadhesive Composite Beads
Author(s): Meenakshi Bhatia, Priya Diman and Prerna
The objective of the study is to prepared, optimize and evaluate metformin hydrochloride loaded OM-SA beads as mucoadhesive drug delivery system. The beads were prepared by ionic gelation method using calcium chloride as a cross linker. The prepared formulation was optimized by using 3-factor-3-level central composite design. The synthesized okra, alginate composite beads were characterized by fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy. The results revealed that okra mucilage/alginate, concentrations of calcium chloride and hardening time exerted significant effect on % entrapment, % release rate, % mucoadhesion, %swelling and % yield. Analysis of Variance (ANOVA) was applied on the % entrapment, % Rel24 and % mucoadhesion and %swelling of beads to s... view more»
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