Journal of Otology & RhinologyISSN: 2324-8785

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Purnima Thakur Author

purnimathakur28@gmail.com 9418141839

Subjects of specialization
Otorhinolaryngology,

Affiliation
Department of , Juntendo University of Medicine, Shizuoka Hospital, Shizuoka, Japan

Biography

Purnima Thakur has worked in department of Otorhinolaryngology, Juntendo University of Medicine, Shizuoka Hospital, Shizuoka, Japan. He has specialized in Otorhinolaryngology in head , neck and throat

Publications

Case Report Open Access

Large Cell Neuroendocrine Carcinoma of the Larynx: A Case Report and Review of Literature

Author(s):

Purnima Thakur*, Shikhar Kumar and Vishal Verma

Laryngeal neuroendocrine carcinomas (LNEC) constitute <1% of all tumours originating from the larynx and are believed to originate from pluripotential stem cells located in the submucosa of the larynx. It is hard to estimate the true incidence of large-cell neuroendocrine carcinoma (LCNEC) because the WHO classification does not make a distinction between atypical carcinoid tumors and large-cell neuroendocrine carcinoma. In the current classification, laryngeal LCNEC is considered synonymous with atypical carcinoid/moderately-differentiated (Grade II) neuroendocrine carcinoma. This distinction is clinically important as the clinical behavior and response to treatment differs greatly between subtypes. We report a rare case of metastatic LCNEC of subglottic region of larynx who is trea... view more»

DOI: 10.4172/2324-8785.1000354

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