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Reza Moghadasali Author
Subjects of specialization
Affiliation
Adolescent and Pediatric Gynecology, Anorexia Nervosa, Biochemistry of Reproductive Science, Biodiversity Management, Biodiversity and Conservation
Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
Biography
Reza Moghadasali has completed my PhD at the age of 35 years from Kharazmi University, Iran. I am the director/assistant professor of Royan Institute, Iran. I have over 22 publications that have been cited over 500 times, and my publication H-index is 10 and has been serving as an editorial board member of reputed Journals
Publications
Short Communication Open Access
Transplantation of mouse induced pluripotent stem cell-derived podocytes in a mouse model of membranous nephropathy attenuates proteinuria
Author(s): Reza Moghadasali, Amin Ahmadi, Hossein Baharvand and Nasser Aghdami
Injury to podocytes is a principle cause for initiation and progression of both immune and non-immune mediated glomerular diseases (GD) that result in proteinuria. Current advances in regenerative medicine shed light on the potential for cell-based therapy to treat several of these disorders. Thus, there is hope that generation and transplantation of podocytes from induced pluripotent stem cells (iPSCs) could potentially provide a curative treatment for glomerulonephritis caused by podocyte injury and loss. In this study, mouse model of membranous nephropathy (MN) was carried out with intravenous administration of anti-podocyte antibody (APA) after subcutaneous pre-immunization. iPSCs were derived from induced anti-podocyte nephropathy (APN) mouse tail-tip fibroblasts (TTFs) by retroviral ... view more»
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