S S Gaikwad Author

Short Communication Open Access

Molecular Epidemiological Analysis of Rabies Virus in Mumbai Region of India

Author(s):

Rajesh Raghunath Pharande, S B Majee, S S Gaikwad, A S Bannalikar, R S Gandge, D G Dighe, S S Moregoankar, A Y
Doiphode, S A Ingle, S Mukherjee and V V Zunjare

Rabies is one of the negligible fatal acute viral disease of the central nervous system, which is a serious public health problem and is responsible for over 30, 000 deaths in Asia and Africa alone.Rabies caused by a neurotropic virus belonging to the Lyssavirusgenus of family Rhabdoviridae. Rabies virus Nucleoprotein (N) gene highly conserved gene mainly used for genetic analysis whereas Glycoprotein (G) plays a critical role in the pathogenesis of the disease. Despite the importance of rabies for animal and human health, little is known about the evolutionary dynamics of Rabies virus in dog populations and patterns of biodiversity. To address these questions on a small scale, a total of 50 dog brain samples suspected for rabies were screened by Seller’s staining test (SST), Mous... view more»

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