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Hindi La Prensa MedicaISSN: 0032-745X
Sahar Aslzadeh Author
Subjects of specialization
Affiliation
Late-onset pompe disease, Motor functions, CPK levels from Tehran Medical Sciences Branch, Enzyme replacement therapy
General Physician, Faculty of Medicine, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran
Biography
Sahar Aslzadeh, belonging to General Physician, Faculty of Medicine, intrested in the field of Enzyme replacement therapy; Late-onset pompe disease; Motor functions; CPK levels from Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran
Publications
Research Article Open Access
Effects of Enzyme Replacement Therapy on the Respiratory and Motor Functions Among Patients with Late-Onset Pompe Disease for Long-Term
Author(s): Khadijeh Haji Naghi Tehrani, Sahar Aslzadeh, Mehrnosh Boroomandpoor, Seyed Hamid Reza Moezzi, Fatemeh Moosavi and Mehdi Vahiddastjerdi
Background: Pompe is a congenital metabolic disorder and muscles involvement that is the most common presentation of it. The late-onset Pompe disease (LOPD) is a type of Pompe according to the age of clinical presentation. In LOPD, the muscles of the trunk and proximal lower extremity have not normal function, and the repertory failure can be happening for these patients. Enzyme replacement therapy (ERT) is a new method for treatment of these patients, but the efficacy and safety of this method are challenging for long-term so that in this pilot study efficacy and safety were evaluated for two years. Methods: In this prospective study, the patients with LOPD included this study, and they received rhGAA every two weeks for two years. In this period the motor and respiratory function of t... view more»
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