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Hindi Clinical Oncology: Case Reports
Satya Das Author
Subjects of specialization
Affiliation
"Cancer Endocrine ,Cancer Gastrointestinal ,Medical Oncology,Metastatic Cancer Stomach,Pancreas Cancer
Assistant Professor of Medicine, and MSCI 1301 Medical Center Drive, Nashville, TN 37232, USA
Biography
"Dr. Das is an Assistant Professor of Medicine in the Department of Medicine Division of Hematology/Oncology at Vanderbilt University Medical Center. His research interests are in the realm of gastrointestinal (GI) cancer, with a focus on neuroendocrine tumors (NETs), and drug development. They specifically focus upon designing early phase studies to take advantage of salvage DNA repair pathway dependence in DNA damage response (DDR) deficient tumors and to overcome the immunosuppressive tumor microenvironment in refractory tumors through immunotherapy combinations. He is the national principal investigator of several DDR focused studies in gastric and gastroesophageal junction (GEJ) adenocarcinoma, neuroendocrine tumors.
Publications
Case Report Open Access
Brachytherapy Boost to Tumor Bed Prior to Adjuvant Chemoradiation in Margin Positive Resected Cholangiocarcinoma
Author(s): Satya Das*, John Kelly Wrigh, Laura Goff, Anuradha Chakravarthy and Emily Chan (USA)
Importance: The role of adjuvant therapy in resected cholangiocarcinoma patients is unproven despite poor survival rates even in completely resected patients. Most relapses occur locally and within a relatively short window from time of resection. R1 resection and lymph node positive patients are particularly at high risk for local relapse. Observation: Adjuvant modalities have not been compared head to head against one another in cholangiocarcinoma patients. The recent phase III PRODIGE 12-ACCORD 18 trial assessing adjuvant chemotherapy with gemcitabine and oxaliplatin in this group of patients was a negative study. Adjuvant radiation has been shown in some retrospective series to improve overall survival in R1 resected and lymph node positive patients. Other retrospective studies sugg... view more»
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